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KMID : 0438219770140020277
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Korea University Medical Journal
1977 Volume.14 No. 2 p.277 ~ p.285
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The effect of hydrotherapy on the clinical course and pH of experimental cutaneous chemical burns
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Abstract
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Accidental contact with chemicals, or their misuse, is prominent among the course of injury and death, and constitutes one of the potential hazards of our modern life.
Most of the skin burns are around the face, neck, chest, and upper extremity; often the eyes are involved resulting in a high percentage of corneal burns and frequently total blindness.
The present mode of treatment for a chemical burn, such as from lye(NaOH) or HCL, is continuous copious irrigation with water.
Author performed experimental studies in 120 mice with the effect of hydrotherapy on the clinical course and pH of experimental cutaneous chemical burns.
Following results were observed;
1. Skin necrosis and eschar formation were more severe in those groups which were irrigated later time after burn.
2 The HCL groups displayed rapidly progressive burn in extent immediately after burn but total degree of eschars were less than the alkali groups. Conversely, in the alkali groups, burns were deceptive; at first their effect appeared slight but they progressed seriously by direct extension.
3 Histological examination of burned area revealed the more prominent changes in those groups burned with alkali (NaOH) and irrigated later time.
4. Changes of cutaneous pH of burned area showed the more severe pH aberration in the NaOH groups. Both groups in the NaOH and the HCL revealed the more severe pH changes in those groups washed later time.
5. The mortality rate in the NaOH groups was higher than the HCL groups.
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